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Test Code DBS1 Diabetes Mellitus Type 1 Evaluation, Serum

Useful For

Distinguishing type 1 from type 2 diabetes mellitus

 

Identifying individuals at risk of type 1 diabetes (including high-risk relatives of patients with diabetes)

 

Predicting future insulin requirement treatment in patients with adult-onset diabetes

Profile Information

Test ID Reporting Name Available Separately Always Performed
DMEI Diabetes Interpretation, S No Yes
GD65S GAD65 Ab Assay, S Yes Yes
INAB Insulin Abs, S Yes Yes
IA2 IA-2 Ab, S Yes Yes
EZNT8 ZnT8 Ab, S Yes Yes

Method Name

GD65S,INAB, IA2: Radioimmunoassay (RIA)

EZNT8: Enzyme-Linked Immunosorbent Assay (ELISA)DMEI: Interpretive Comments

Reporting Name

Diabetes Mellitus Type 1 Evaluation

Specimen Type

Serum


Specimen Required


Container/Tube: 

Preferred: Red top

Acceptable: Serum gel

Specimen Volume: 4 mL


Specimen Minimum Volume

2 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Refrigerated (preferred) 28 days
  Frozen  28 days
  Ambient  72 hours

Reference Values

GLUTAMIC ACID DECARBOXYLASE (GAD65) ANTIBODY

≤0.02 nmol/L

Reference values apply to all ages.

 INSULIN ANTIBODIES

≤0.02 nmol/L

Reference values apply to all ages.

 ISLET ANTIGEN 2 (IA-2) ANTIBODY

≤0.02 nmol/L

Reference values apply to all ages.

ZINC Transporter 8 (ZnT8) ANTIBODY

< 15.0 U/mL

Reference values apply to all ages.

Day(s) and Time(s) Performed

Monday through Thursday, Sunday; 10 p.m.

GAD65 antibody: Monday through Friday; 4 a.m.; 4 p.m.

Insulin antibodies: Monday, Wednesday, Friday; 4 a.m.

IA-2 antibody: Tuesday, Thursday; 4 a.m.

Zinc Transporter 8 Antibody: Tuesday and Thursday, 10 a.m.

Performing Laboratory

Mayo Medical Laboratories in Rochester

Test Classification

See Individual Components

CPT Code Information

86337-Insulin antibodies

86341 x3-Islet cell antibody

LOINC Code Information

Test ID Test Order Name Order LOINC Value
DBS1 Diabetes Mellitus Type 1 Evaluation In Process

 

Result ID Test Result Name Result LOINC Value
81596 GAD65 Ab Assay, S 30347-9
89588 IA-2 Ab, S 81155-4
8666 Insulin Abs, S 60463-7
34268 Diabetes Interpretation, S 69048-7
64926 ZnT8 Ab, S In Process