Sign in →

Test Code FRDIG Digoxin, Free, Serum

Reporting Name

Digoxin, Free, S

Useful For

Evaluating recrudescent (breakthrough) digoxin toxicity in renal-failure patients

 

Assessing the need for more antidigoxin Fab to be administered

 

Deciding when to reintroduce digoxin therapy

 

Monitoring patients with possible digoxin-like immunoreactive factors (DLIFs)

Performing Laboratory

Mayo Medical Laboratories in Rochester

Specimen Type

Serum


Specimen Required


Container/Tube: 

Preferred: Serum gel

Acceptable: Red top

Specimen Volume: 1 mL

Collection Instructions:

1. Draw blood 6 to 8 hours after last dose of digoxin.

2. Serum gel tubes should be centrifuged within 2 hours of collection.

3. Red-top tubes should be centrifuged and aliquoted within 2 hours of collection.


Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Refrigerated (preferred) 7 days
  Frozen  180 days

Reference Values

<16 years:

Therapeutic ranges have not been established for patients who are under 16 years of age. In adults, the suggested serum free digoxin therapeutic range is 0.4-0.9 ng/mL.

Toxic concentration: ≥3.0

 

≥16 years:

0.4-0.9 ng/mL   

Toxic concentration: ≥3.0 ng/ mL

Day(s) and Time(s) Performed

Monday through Sunday; Continuously

Test Classification

This test has been modified from the manufacturer's instructions. Its performance characteristics were determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

CPT Code Information

80163

LOINC Code Information

Test ID Test Order Name Order LOINC Value
FRDIG Digoxin, Free, S 3562-6

 

Result ID Test Result Name Result LOINC Value
FRDIG Digoxin, Free, S 3562-6

Method Name

Ultrafiltration Followed by Electrochemiluminescent Immunoassay

Forms

If not ordering electronically, complete, print, and send a Cardiovascular Test Request Form (T724) with the specimen (http://www.mayomedicallaboratories.com/it-mmfiles/cardiovascular-request-form.pdf).