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Test Code FEC Iron and Total Iron-Binding Capacity, Serum

Reporting Name

Iron and Total Fe Binding Cap, S

Useful For

Screening for chronic iron overload diseases, particularly hereditary hemochromatosis

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Specimen Type


Necessary Information

Patient's age and sex are required.

Specimen Required

Patient Preparation:

1. Fasting (12 hours)

2. Iron-containing supplements should be avoided for 24 hours prior to draw.


Preferred: Serum gel

Acceptable: Red top

Specimen Volume: 1 mL

Collection Instructions:

1. Draw blood before 12 noon (preferred).

2. Serum gel tubes should be centrifuged within 2 hours of collection.

3. Red-top tubes should be centrifuged and aliquoted within 2 hours of collection.

Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 7 days
  Frozen  180 days

Reference Values


Males: 50-150 mcg/dL

Females: 35-145 mcg/dL



250-400 mcg/dL




Day(s) and Time(s) Performed

Monday through Saturday; Continuously

Test Classification

This test has been cleared or approved by the U.S. Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information


83550-Iron-binding capacity

LOINC Code Information

Test ID Test Order Name Order LOINC Value
FEC Iron and Total Fe Binding Cap, S 50190-8


Result ID Test Result Name Result LOINC Value
IRON Iron 2498-4
TIBC Total Iron Binding Capacity 2500-7
SAT Percent Saturation 2502-3

Testing Algorithm

See Hereditary Hemochromatosis Algorithm in Special Instructions.

Method Name

Immunoturbidimetric Assay


If not ordering electronically, complete, print, and send a Benign Hematology Test Request Form (T755) with the specimen.