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Test Code LTE4 Leukotriene E4, Urine

Useful For

Evaluating patients suspected of having systemic mastocytosis

 

Identification of aspirin sensitivity in patient respiratory diagnoses

Testing Algorithm

When leukotriene E4 testing is performed, urine creatinine will always be performed at no additional charge.

Reporting Name

Leukotriene E4, U

Specimen Type

Urine


Specimen Required


Submit only 1 of the following specimens:

 

Patient Preparation: Patients taking 5-lipoxygenase inhibitor Zileuton/Zyflo may have decreased concentrations of leukotriene E4 (LTE4) if dosage has not been discontinued for 48 hours. If possible, discontinue for 48 hours before testing.

 

Preferred: 24-hour urine collection

Container/Tube: Plastic, 5-mL tube (T465)

Specimen Volume: 4 mL

Collection Instructions:

1. Collect urine for 24 hours.

2. Refrigerate specimen during collection, aliquot 4 mL of urine into plastic tube, and send specimen refrigerated.

Additional Information: See Urine Preservatives-Collection and Transportation for 24-Hour Urine Specimens in Special Instructions for multiple collections.

 

Acceptable: Random collection

Container/Tube: Plastic, 5-mL tube (T465)

Specimen Volume: 4 mL

Collection Instructions:

1. Collect a random urine specimen. 

2. Refrigerate specimen after collection and send specimen refrigerated or frozen; do not add any preservative.


Specimen Minimum Volume

1 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Urine Refrigerated (preferred) 7 days
  Frozen  30 days
  Ambient  24 hours

Reference Values

≤104 pg/mg creatinine

Day(s) and Time(s) Performed

Tuesday, Friday; 11 a.m.

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

CPT Code Information

82542

LOINC Code Information

Test ID Test Order Name Order LOINC Value
LTE4 Leukotriene E4, U 33343-5

 

Result ID Test Result Name Result LOINC Value
62530 Leukotriene E4, U 33343-5

Method Name

LTE4: Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)

AACT: Enzymatic Colorimetric Assay

Urine Preservative Collection Options

Note: The addition of preservative or application of temperature controls must occur within 4 hours of completion of the collection.

Ambient

OK

Refrigerate

Preferred

Frozen

OK

50% Acetic Acid

OK

Boric Acid

OK

Diazolidinyl Urea

No

6M Hydrochloric Acid

No

6M Nitric Acid

No

Sodium Carbonate

OK

Thymol

No

Toluene

No