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Test Code OPRMO Opioid Receptor, Mu 1 (OPRM1) Genotype for Naltrexone Efficacy, Saliva

Reporting Name

OPRM1 Genotype, Naltrexone, Saliva

Useful For

Identifying individuals with a higher probability of successful treatment for alcoholism with naltrexone


Genotyping patients who prefer not to have venipuncture done

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Specimen Type


Specimen Required

Multiple saliva genotype tests can be performed on a single specimen after a single extraction. See Multiple Saliva Genotype Tests in Special Instructions for a list of tests that can be ordered together.


Supplies: DNA Self-Collection Kit (T651: fees apply)

Container/Tube: Oragene DNA Self-Collection Kit (T651)

Specimen Volume: Full tube

Collection Instructions:

1. Fill tube to line.

2. Send specimen in original container per kit instructions.

Specimen Minimum Volume

1 mL

Specimen Stability Information

Specimen Type Temperature Time
Saliva Ambient

Reference Values

An interpretive report will be provided.

Day(s) and Time(s) Performed

Tuesday; 8 a.m

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

CPT Code Information


LOINC Code Information

Test ID Test Order Name Order LOINC Value
OPRMO OPRM1 Genotype, Naltrexone, Saliva In Process


Result ID Test Result Name Result LOINC Value
33034 OPRM1 Result 82939-0
33035 OPRM1 Reviewed by 18771-6
33036 OPRM1 Interpretation 69047-9

Method Name

Polymerase Chain Reaction (PCR) 5'-Nuclease End-point Allelic Discrimination Analysis


1. New York Clients-Informed consent is required. Please document on the request form or electronic order that a copy is on file. An Informed Consent for Genetic Testing (T576) is available in Special Instructions.

2. If not ordering electronically, complete, print, and send a Pharmacogenomics Test Request (T797) with the specimen.