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Test Code RESPM Respiratory Pathogen Panel, PCR, Nasopharyngeal

Advisory Information

This assay is not predicted to detect SARS-coronavirus (CoV), MERS-CoV, or the virus (SARS-CoV-2) causing coronavirus disease-2019 (COVID-19).


This test is not intended for otherwise healthy, immunocompetent patients who are likely to have a mild, self-limited respiratory infection. If testing is desired, these patients should be tested using the more targeted diagnostic assays based on their exposure history and clinical presentation.

-FLUNP / Influenza Virus Type A and Type B, and Respiratory Syncytial Virus (RSV), Molecular Detection, PCR, Nasopharyngeal Swab

-BPRP / Bordetella pertussis and Bordetella parapertussis, Molecular Detection, PCR

-MPRP / Mycoplasma pneumoniae, Molecular Detection, PCR


It is not recommended that the following tests be concomitantly ordered when this test is ordered:

-FLUNP / Influenza Virus Type A and Type B, and Respiratory Syncytial Virus (RSV), Molecular Detection, PCR, Nasopharyngeal Swab

-LADV / Adenovirus, Molecular Detection, PCR, Varies

-LENT / Enterovirus, Molecular Detection, PCR, Varies

-BPRP / Bordetella pertussis and Bordetella parapertussis, Molecular Detection, PCR, Varies

-MPRP / Mycoplasma pneumoniae, Molecular Detection, PCR, Varies


This test is appropriate for nasopharyngeal swabs only. For bronchoalveolar lavage or bronchial washings specimens, order RESLR / Respiratory Pathogen Panel, PCR, Varies.

Shipping Instructions

Specimens that cannot be shipped refrigerated to Mayo Clinic Laboratories within 3 days (72 hours) should be frozen prior to shipment. Specimens received older than 72 hours (refrigerated) or older than 30 days (frozen) will be canceled.

Specimen Required


Nasopharyngeal Swab (Rayon Mini-Tip Swab) (T515)

M4-RT media (T605)

Specimen Type: Nasopharyngeal Swab

Container/Tube: Culture transport swab and Viral Transport medium (eg, M4, M4-RT, M5, M6, universal transport medium). See Collection Instructions.

Specimen Volume: Entire collection/1 swab

Collection Instructions: Nasopharyngeal swab specimens should be collected according to standard technique and immediately placed into viral transport media and submitted for testing.


If not ordering electronically, complete, print, and send a Microbiology Test Request (T244) with the specimen.

Useful For

Rapid detection of respiratory infections caused by the following:


-Coronavirus (serotypes HKU1, NL63, 229E, OC43)

-Human metapneumovirus

-Human rhinovirus/enterovirus

-Influenza A (H1, H1-2009, H3)

-Influenza B

-Parainfluenza virus (serotypes 1-4)

-Respiratory syncytial virus (RSV)

-Bordetella pertussis

-Bordetella parapertussis

-Chlamydophila pneumoniae

-Mycoplasmoides pneumoniae


This test is not recommended as a test of cure.

Method Name

Multiplex Polymerase Chain Reaction (PCR)

Reporting Name

Respiratory Pathogen Panel, PCR, NP

Specimen Type


Specimen Minimum Volume

Nasopharyngeal swab in minimum volume of 1 mL of viral transport media (eg, M4-RT or M5)

Specimen Stability Information

Specimen Type Temperature Time Special Container
Varies Refrigerated (preferred) 72 hours
  Frozen  30 days
  Ambient  4 hours

Reference Values

Negative (for all targets)

Day(s) and Time(s) Performed

Monday through Sunday

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test has been cleared or approved by the U.S. Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information


LOINC Code Information

Test ID Test Order Name Order LOINC Value
RESPM Respiratory Pathogen Panel, PCR, NP 82159-5


Result ID Test Result Name Result LOINC Value
SS021 Specimen Source 31208-2
36086 Adenovirus 82160-3
36087 Coronavirus 229E 82163-7
36088 Coronavirus HKU1 82161-1
36089 Coronavirus NL63 82162-9
36090 Coronavirus OC43 82164-5
36091 Human Rhinovirus/ Enterovirus 82175-1
36093 Human Metapneumovirus 82165-2
36094 Influenza A 82166-0
36095 Influenza B 82170-2
36096 Parainfluenza Virus 1 82171-0
36097 Parainfluenza Virus 2 82172-8
36098 Parainfluenza Virus 3 82173-6
36099 Parainfluenza Virus 4 82174-4
36100 Respiratory Syncytial Virus 82176-9
36101 Bordetella pertussis 82179-3
607058 Bordetella parapertussis 87621-9
36102 Chlamydophila pneumoniae 82178-5
36103 Mycoplasmoides (Mycoplasma) pneumoniae 82177-7
36312 Interpretation 59464-8