Test Code ACRNS Acylcarnitines, Quantitative, Serum
Necessary Information
1. Patient's age is required.
2. Include family history, clinical condition (asymptomatic or acute episode), diet, and drug therapy information.
Specimen Required
Specimen Type: Serum
Collection Container/Tube:
Preferred: Red top
Acceptable: Serum gel
Submission Container/Tube: Plastic vial
Specimen Volume: 0.1 mL
Collection Instructions: Draw specimen just prior to a scheduled meal or feeding.
Useful For
Diagnosis of fatty acid oxidation disorders and several organic acidurias in serum specimens
Evaluating treatment during follow-up of patients with fatty acid beta-oxidation disorders and several organic acidurias
Testing Algorithm
The following algorithms are available in Special Instructions:
-Newborn Screening Follow-up for Elevations of C8, C6, and C10 Acylcarnitines (also applies to any plasma or serum C8, C6, and C10 acylcarnitine elevations)
-Newborn Screening Follow-up for Isolated C4 Acylcarnitine Elevations (also applies to any plasma or serum C4 acylcarnitine elevation)
-Newborn Screening Follow-up for Isolated C5 Acylcarnitine Elevations (also applies to any plasma or serum C5 acylcarnitine elevation)
Special Instructions
- Newborn Screening Follow-up for Isolated C4 Acylcarnitine Elevations (also applies to any plasma or serum C4 acylcarnitine elevations)
- Newborn Screening Follow-up for Elevations of C8, C6, and C10 Acylcarnitine Elevations (also applies to any plasma or serum C8, C6, and C10 acylcarnitine elevations)
- Newborn Screening Follow-up for Isolated C5 Acylcarnitines Elevations (also applies to any plasma or serum C5 acylcarnitine elevations)
Method Name
Flow Injection Analysis-Tandem Mass Spectrometry (FIA-MS/MS)
Reporting Name
Acylcarnitines, Quantitative, SSpecimen Type
SerumSpecimen Minimum Volume
0.04 mL
Specimen Stability Information
Specimen Type | Temperature | Time |
---|---|---|
Serum | Frozen (preferred) | 60 days |
Refrigerated | 21 days | |
Ambient | 72 hours |
Reference Values
≤7 days (nmol/mL) |
8 days-7 years (nmol/mL) |
≥8 years (nmol/mL) |
|
Acetylcarnitine, C2 |
2.14-15.89 |
2.00-27.57 |
2.00-17.83 |
Acrylylcarnitine, C3:1 |
<0.04 |
<0.05 |
<0.07 |
Propionylcarnitine, C3 |
<0.55 |
<1.78 |
<0.88 |
Formiminoglutamate, FIGLU |
<0.43 |
<0.08 |
<0.14 |
Iso-/Butyrylcarnitine, C4 |
<0.46 |
<1.06 |
<0.83 |
Tiglylcarnitine, C5:1 |
<0.05 |
<0.09 |
<0.11 |
Isovaleryl-/2-Methylbutyrylcarn C5 |
<0.38 |
<0.63 |
<0.51 |
3-OH-iso-/butyrylcarnitine, C4-OH |
<0.13 |
<0.51 |
<0.18 |
Hexenoylcarnitine, C6:1 |
<0.12 |
<0.10 |
<0.15 |
Hexanoylcarnitine, C6 |
<0.14 |
<0.23 |
<0.17 |
3-OH-isovalerylcarnitine, C5-OH |
<0.08 |
<0.12 |
<0.10 |
Benzoylcarnitine |
<0.13 |
<0.07 |
<0.10 |
Heptanoylcarnitine, C7 |
<0.05 |
<0.05 |
<0.06 |
3-OH-hexanoylcarnitine, C6-OH |
<0.08 |
<0.19 |
<0.09 |
Phenylacetylcarnitine |
<0.15 |
<0.22 |
<0.29 |
Salicylcarnitine |
<0.08 |
<0.09 |
<0.09 |
Octenoylcarnitine, C8:1 |
<0.48 |
<0.91 |
<0.88 |
Octanoylcarnitine, C8 |
<0.19 |
<0.45 |
<0.78 |
Malonylcarnitine, C3-DC |
<0.09 |
<0.14 |
<0.26 |
Decadienoylcarnitine, C10:2 |
<0.11 |
<0.12 |
<0.26 |
Decenoylcarnitine, C10:1 |
<0.25 |
<0.46 |
<0.47 |
Decanoylcarnitine, C10 |
<0.27 |
<0.91 |
<0.88 |
Methylmalonyl-/succinylcarn, C4-DC |
<0.05 |
<0.05 |
<0.05 |
3-OH-decenoylcarnitine, C10:1-OH |
<0.12 |
<0.12 |
<0.13 |
Glutarylcarnitine, C5-DC |
<0.06 |
<0.10 |
<0.11 |
Dodecenoylcarnitine, C12:1 |
<0.19 |
<0.37 |
<0.35 |
Dodecanoylcarnitine, C12 |
<0.18 |
<0.35 |
<0.26 |
3-Methylglutarylcarnitine, C6-DC |
<0.28 |
<0.21 |
<0.43 |
3-OH-dodecenoylcarnitine, C12:1-OH |
<0.11 |
<0.10 |
<0.13 |
3-OH-dodecanoylcarnitine, C12-OH |
<0.06 |
<0.09 |
<0.08 |
Tetradecadienoylcarnitine, C14:2 |
<0.09 |
<0.13 |
<0.18 |
Tetradecenoylcarnitine, C14:1 |
<0.16 |
<0.35 |
<0.24 |
Tetradecanoylcarnitine, C14 |
<0.11 |
<0.15 |
<0.12 |
Octanedioylcarnitine, C8-DC |
<0.25 |
<0.19 |
<0.19 |
3-OH-tetradecenoylcarnitine C14:1OH |
<0.06 |
<0.18 |
<0.13 |
3-OH-tetradecanoylcarnitine, C14-OH |
<0.04 |
<0.05 |
<0.08 |
Hexadecenoylcarnitine, C16:1 |
<0.15 |
<0.21 |
<0.10 |
Hexadecanoylcarnitine, C16 |
<0.36 |
<0.52 |
<0.23 |
3-OH-hexadecenoylcarnitine,C16:1-OH |
<0.78 |
<0.36 |
<0.06 |
3-OH-hexadecanoylcarnitine, C16-OH |
<0.10 |
<0.07 |
<0.06 |
Octadecadienoylcarnitine, C18:2 |
<0.12 |
<0.31 |
<0.24 |
Octadecenoylcarnitine, C18:1 |
<0.25 |
<0.45 |
<0.39 |
Octadecanoylcarnitine, C18 |
<0.10 |
<0.12 |
<0.14 |
Dodecanedioylcarnitine, C12-DC |
<0.10 |
<0.04 |
<0.04 |
3-OH-octadecadienoylcarn, C18:2-OH |
<0.04 |
<0.06 |
<0.06 |
3-OH-octadecenoylcarnitine C18:1-OH |
<0.03 |
<0.04 |
<0.06 |
3-OH-octadecanoylcarnitine, C18-OH |
<0.03 |
<0.05 |
<0.03 |
Day(s) and Time(s) Performed
Monday through Friday; 8 a.m.
Performing Laboratory

Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.CPT Code Information
82017
LOINC Code Information
Test ID | Test Order Name | Order LOINC Value |
---|---|---|
ACRNS | Acylcarnitines, Quantitative, S | 43433-2 |
Result ID | Test Result Name | Result LOINC Value |
---|---|---|
92134 | Acetylcarnitine, C2 | 30191-1 |
92135 | Acrylylcarnitine, C3:1 | 43235-1 |
92136 | Propionylcarnitine, C3 | 30551-6 |
92137 | Formiminoglutamate, FIGLU | 79628-4 |
92138 | Iso-/Butyrylcarnitine, C4 | 35655-0 |
92139 | Tiglylcarnitine, C5:1 | 51416-6 |
92140 | Isovaleryl-/2-Methylbutyrylcarn C5 | 30531-8 |
92141 | 3-OH-iso-/butyrylcarnitine, C4-OH | 39000-5 |
92142 | Hexenoylcarnitine, C6:1 | 74540-6 |
92143 | Hexanoylcarnitine, C6 | 30358-6 |
92144 | 3-OH-isovalerylcarnitine, C5-OH | 39001-3 |
92145 | Benzoylcarnitine | 39615-0 |
92146 | Heptanoylcarnitine, C7 | 55871-8 |
92147 | 3-OH-hexanoylcarnitine, C6-OH | 30236-4 |
92148 | Phenylacetylcarnitine | 90237-9 |
92149 | Salicylcarnitine | 90238-7 |
92150 | Octenoylcarnitine, C8:1 | 30541-7 |
92151 | Octanoylcarnitine, C8 | 30540-9 |
92152 | Malonylcarnitine, C3-DC | 55940-1 |
92153 | Decadienoylcarnitine, C10:2 | 53471-9 |
92154 | Decenoylcarnitine, C10:1 | 30328-9 |
92155 | Decanoylcarnitine, C10 | 30327-1 |
92156 | Methylmalonyl-/succinylcarn, C4-DC | 51415-8 |
92157 | 3-OH-decenoylcarnitine, C10:1-OH | 82478-9 |
92158 | Glutarylcarnitine, C5-DC | 30349-5 |
92159 | Dodecenoylcarnitine, C12:1 | 30332-1 |
92160 | Dodecanoylcarnitine, C12 | 30331-3 |
92161 | 3-Methylglutarylcarnitine, C6-DC | 39002-1 |
92162 | 3-OH-dodecenoylcarnitine, C12:1-OH | 59195-8 |
92163 | 3-OH-dodecanoylcarnitine, C12-OH | 30233-1 |
92164 | Tetradecadienoylcarnitine, C14:2 | 30564-9 |
92165 | Tetradecenoylcarnitine, C14:1 | 30566-4 |
92166 | Tetradecanoylcarnitine, C14 | 30565-6 |
92167 | Octanedioylcarnitine, C8-DC | 39014-6 |
92168 | 3-OH-tetradecenoylcarnitine C14:1OH | 30190-3 |
92169 | 3-OH-tetradecanoylcarnitine, C14-OH | 30238-0 |
92170 | Hexadecenoylcarnitine, C16:1 | 30357-8 |
92171 | Hexadecanoylcarnitine, C16 | 30356-0 |
92172 | 3-OH-hexadecenoylcarnitine,C16:1-OH | 30235-6 |
92173 | 3-OH-hexadecanoylcarnitine, C16-OH | 30234-9 |
92174 | Octadecadienoylcarnitine, C18:2 | 30534-2 |
92175 | Octadecenoylcarnitine, C18:1 | 30542-5 |
92176 | Octadecanoylcarnitine, C18 | 30560-7 |
92177 | Dodecanedioylcarnitine, C12-DC | 55855-1 |
92178 | 3-OH-octadecadienoylcarn, C18:2-OH | 30237-2 |
92179 | 3-OH-octadecenoylcarnitine C18:1-OH | 30312-3 |
92180 | 3-OH-octadecanoylcarnitine, C18-OH | 35656-8 |
92181 | Comment (ACRNS) | 46252-3 |
Forms
If not ordering electronically, complete, print, and send an Inborn Errors of Metabolism Test Request (T798) with the specimen.