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Test Code HYOX Hyperoxaluria Panel, Urine

Reporting Name

Hyperoxaluria Panel, U

Useful For

Distinguishing between primary and secondary hyperoxaluria

 

Distinguishing between primary hyperoxaluria types 1, 2, and 3

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Specimen Type

Urine


Specimen Required


Supplies: Urine Tubes, 10 mL (T068)

Container/Tube: Plastic, 10-mL urine tube

Specimen Volume: 10 mL

Collection Instructions:

1. Have patient void the first-morning specimen, then collect specimen within 2 hours of first-morning void.

2. No preservative.

3. Immediately freeze specimen.


Specimen Minimum Volume

1.1 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Urine Frozen (preferred) 90 days
  Refrigerated  14 days

Special Instructions

Reference Values

REPORTING/INTERPRETING RESULTS

Reference Intervals (Normal Ranges):

 

GLYCOLATE

≤17 years: ≤75 mg/g creatinine

≥18 years: ≤50 mg/g creatinine

 

GLYCERATE

≤31 days: ≤75 mg/g creatinine

32 days - 4 years: ≤125 mg/g creatinine

5 - 10 years: ≤55 mg/g creatinine

≥11 years: ≤25 mg/g creatinine

 

OXALATE

≤6 months: ≤400 mg/g creatinine

7 months - 1 year: ≤300 mg/g creatinine

2 - 6 years: ≤150 mg/g creatinine

7 - 10 years: ≤100 mg/g creatinine

≥11 years: ≤75 mg/g creatinine

 

4-HYDROXY-2-OXOGLUTARATE (HOG)

≤10 mg/g creatinine

Day(s) and Time(s) Performed

Thursday; 8 a.m.

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

CPT Code Information

82542

LOINC Code Information

Test ID Test Order Name Order LOINC Value
HYOX Hyperoxaluria Panel, U 53710-0

 

Result ID Test Result Name Result LOINC Value
50592 Glycolate 13751-3
50593 Glycerate 13749-7
50594 Oxalate 13483-3
38049 4-hydroxy-2-oxoglutarate 13678-8
29982 Interpretation 59462-2
29984 Reviewed By 18771-6

Testing Algorithm

See Hyperoxaluria Diagnostic Algorithm in Special Instructions.

Method Name

Gas Chromatography-Mass Spectrometry (GC-MS)

Forms

If not ordering electronically, complete, print, and send 1 of the following forms with the specimen:

-Inborn Errors of Metabolism Test Request (T798)

-Renal Diagnostics Test Request (T830)