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Test Code PCHE1 Pseudocholinesterase, Total, Serum

Necessary Information

Patient's age and sex are required.

Specimen Required

Patient Preparation: For cases of prolonged apnea following surgery, wait at least 24 hours before obtaining specimen.

Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL

Collection Instructions:

1. Serum gel tubes should be centrifuged within 2 hours of collection.

2. Red-top tubes should be centrifuged and the serum aliquoted into a plastic vial within 2 hours of collection.

Useful For

Monitoring exposure to organophosphorus insecticides


Monitoring patients with liver disease, particularly those undergoing liver transplantation


Identifying patients who are homozygous or heterozygous for an atypical gene and have low levels of pseudocholinesterase


This tests is not useful for the differential diagnosis of jaundice.

Method Name

Colorimetric Assay

Reporting Name

Pseudocholinesterase, Total, S

Specimen Type


Specimen Minimum Volume

0.25 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 14 days
  Frozen  365 days
  Ambient  24 hours

Reference Values


5320-12,920 U/L


0-15 years: 5320-12,920 U/L

16-39 years: 4260-11,250 U/L

40-41 years: 5320-12,920 U/L

≥42 years: 5320-12,920 U/L

Note: Females age 18-41 years who are pregnant or taking hormonal contraceptives, the reference interval is 3650-9120 U/L.

Day(s) Performed

Monday through Friday

Report Available

Same day/1 to 3 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information


LOINC Code Information

Test ID Test Order Name Order LOINC Value
PCHE1 Pseudocholinesterase, Total, S 2098-2


Result ID Test Result Name Result LOINC Value
PCHE1 Pseudocholinesterase, Total, S 2098-2