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HelpTest Code PHSP Prenatal Hepatitis Evaluation, Serum
Reporting Name
Prenatal Hepatitis EvaluationProfile Information
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| HBAGP | HBs Antigen Prenatal, S | Yes | Yes |
| HCVSP | HCV Ab Scrn Prenatal, S | Yes | Yes |
Reflex Tests
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| EAG | Hepatitis Be Ag, S | Yes | No |
| HEAB | HBe Antibody, S | Yes | No |
| HBNTP | HBs Ag Confirmation Prenatal, S | No | No |
| HCVRP | HCV RNA Detect/Quant Prenatal, S | Yes | No |
Testing Algorithm
If the hepatitis B virus surface antigen (HBsAg) result is reactive, then HBsAg confirmation testing will be performed at an additional charge. If the HBsAg confirmation result is positive, then HBe Ag and HBe antibody testing will be performed at an additional charge.
If the hepatitis C virus (HCV) antibody screen is reactive, then HCV RNA testing by reverse transcriptase-polymerase chain reaction will be performed at an additional charge.
For more information see Hepatitis B: Testing Algorithm for Screening, Diagnosis, and Management.
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Specimen Type
Serum SSTNecessary Information
Date of collection is required.
Specimen Required
Patient Preparation: For 24 hours before specimen collection, patient should not take multivitamins or dietary supplements (eg, hair, skin, and nail supplements) containing biotin (vitamin B7).
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Collection Container/Tube: Serum gel (red-top tubes are not acceptable)
Submission Container/Tube: Plastic vial
Specimen Volume: 2.2 mL
Collection Instructions:
1. Centrifuge blood collection tube per manufacturer's instructions (eg, centrifuge and aliquot within 2 hours of collection for BD Vacutainer tubes).
2. Aliquot serum into a plastic vial and ship frozen (preferred).
Specimen Minimum Volume
1.6 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum SST | Frozen (preferred) | 84 days | |
| Refrigerated | 6 days |
Special Instructions
Reference Values
HEPATITIS B VIRUS SURFACE ANTIGEN
Negative
HEPATITIS C VIRUS ANTIBODY
Negative
Day(s) Performed
Monday through Saturday
Test Classification
This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.CPT Code Information
87340
86803
G0472 (if appropriate for government payers)
87522 (if appropriate)
86707 (if appropriate)
87341 (if appropriate)
87350 (if appropriate)
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| PHSP | Prenatal Hepatitis Evaluation | 101653-4 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| HBSAP | HBs Antigen Prenatal, S | 5196-1 |
| HCVA6 | HCV Ab Prenatal, S | 40726-2 |
Report Available
Same day/1 to 4 daysMethod Name
Electrochemiluminescence Immunoassay (ECLIA)
Useful For
Screening pregnant women for chronic hepatitis B and hepatitis C in primary care settings, with or without risk factors for hepatitis C
Determining the level of infectivity of chronic hepatitis B in pregnant women
This test is not useful for diagnosis of hepatitis B during the "window period" of acute hepatitis B virus infection (ie, after disappearance of hepatitis B surface antigen and prior to appearance of hepatitis B surface antibody).
This test should not be used as a screening test for hepatitis C in blood or human cells/tissue donors.
This test profile is not useful for detection or diagnosis of acute hepatitis C virus (HCV) in pregnancy, since HCV antibodies may not be detectable until after 2 months following exposure, and HCV RNA testing is not performed on specimens with negative HCV antibody screening test results.
Forms
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