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Test Code TABSU Targeted Benzodiazepine Screen, Urine


Specimen Required


Only orderable as part of profile. For more information see:

CSMP / Controlled Substance Monitoring Panel, Urine

TBSU / Targeted Benzodiazepine Screen, Urine

 

Supplies: Aliquot Tube, 5 mL (T465)

Collection Container/Tube: Plastic urine container

Submission Container/Tube: Plastic, 5-mL tube

Specimen Volume: 3 mL

Collection Instructions:

1. Collect a random urine specimen.

2. No preservative


Useful For

High-resolution accurate mass method to qualitatively (present vs. not detected) identify 27 benzodiazepine compounds (parent drug and metabolites) in urine to help determine compliance or identify illicit benzodiazepine drug use

Method Name

Only orderable as part of profile. For more information see:

CSMP / Controlled Substance Monitoring Panel, Urine

TBSU / Targeted Benzodiazepine Screen, Urine

 

Liquid Chromatography-Tandem Mass Spectrometry, High Resolution Accurate Mass (LC-MS/MS HRAM)

Reporting Name

Targeted Benzodiazepine Screen, U

Specimen Type

Urine

Specimen Minimum Volume

1 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Urine Refrigerated (preferred) 14 days
  Frozen  28 days
  Ambient  72 hours

Reference Values

Only orderable as part of profile. For more information see:

CSMP / Controlled Substance Monitoring Panel, Urine

TBSU / Targeted Benzodiazepine Screen, Urine

 

Not Detected

 

Cutoff concentrations:

 

Alprazolam: 10 ng/mL

Alpha-Hydroxyalprazolam: 10 ng/mL

Alpha-Hydroxyalprazolam Glucuronide: 50 ng/mL

Chlordiazepoxide: 10 ng/mL

Clobazam: 10 ng/mL

N-Desmethylclobazam: 200 ng/mL

Clonazepam: 10 ng/mL

7-aminoclonazepam: 10 ng/mL

Diazepam: 10 ng/mL

Nordiazepam: 10 ng/mL

Flunitrazepam: 10 ng/mL

7-aminoflunitrazepam: 10 ng/mL

Flurazepam: 10 ng/mL

2-Hydroxy Ethyl Flurazepam: 10 ng/mL

Lorazepam: 10 ng/mL

Lorazepam Glucuronide: 50 ng/mL

Midazolam: 10 ng/mL

Alpha-Hydroxy Midazolam: 10 ng/mL

Oxazepam: 10 ng/mL

Oxazepam Glucuronide: 50 ng/mL

Prazepam: 10 ng/mL

Temazepam: 10 ng/mL

Temazepam Glucuronide: 50 ng/mL

Triazolam: 10 ng/mL

Alpha-Hydroxy Triazolam: 10 ng/mL

Zolpidem: 10 ng/mL

Zolpidem Phenyl-4-Carboxylic acid: 10 ng/mL

Day(s) and Time(s) Performed

Monday through Friday; Varies

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

CPT Code Information

80347

G0480 (if appropriate)

LOINC Code Information

Test ID Test Order Name Order LOINC Value
TABSU Targeted Benzodiazepine Screen, U 94117-9

 

Result ID Test Result Name Result LOINC Value
604871 Alprazolam 94116-1
604867 Alpha-Hydroxyalprazolam 19325-0
604891 Alpha-Hydroxyalprazolam Glucuronide 94115-3
604872 Chlordiazepoxide 19385-4
604889 Clobazam 94114-6
604890 N-Desmethylclobazam 94113-8
604873 Clonazepam 19399-5
604267 7-aminoclonazepam 94112-0
604874 Diazepam 19443-1
604880 Nordiazepam 19624-6
604875 Flunitrazepam 19466-2
604866 7-aminoflunitrazepam 94111-2
604876 Flurazepam 19474-6
604868 2-Hydroxy Ethyl Flurazepam 94110-4
604877 Lorazepam 19520-6
604878 Lorazepam Glucuronide 94109-6
604879 Midazolam 19585-9
604869 Alpha-Hydroxy Midazolam 94108-8
604881 Oxazepam 19638-6
604882 Oxazepam Glucuronide 94107-0
604883 Prazepam 19678-2
604884 Temazepam 19698-0
604885 Temazepam Glucuronide 94106-2
604886 Triazolam 19714-5
604870 Alpha-Hydroxy Triazolam 94105-4
604887 Zolpidem 94104-7
604888 Zolpidem Phenyl-4-Carboxylic acid 94103-9
604949 Benzodiazepine Interpretation 69050-3